Receiving a diagnosis of Overt Hepatic Encephalopathy (OHE) can bring a mix of emotions and questions. OHE is a serious brain dysfunction that arises from advanced chronic liver disease, specifically cirrhosis. It can manifest in various physical and mental symptoms, such as tremors, confusion, and forgetfulness. When these symptoms become significantly pronounced, they are classified as “overt.”
What is Overt Hepatic Encephalopathy (OHE)?
Essentially, OHE occurs when a damaged liver can no longer effectively filter toxins from the blood. These toxins can then reach the brain, impacting its function. The symptoms can range from mild cognitive changes to severe confusion and disorientation, significantly affecting a person’s daily life and independence.
For individuals diagnosed with OHE, managing the condition involves a multi-faceted approach. Keeping a close eye on your symptoms and diligently following your prescribed treatment plan are crucial steps in reducing the frequency and severity of OHE episodes. Regular, honest conversations with your healthcare provider about your symptoms, lifestyle, and overall health are paramount to assessing your risk and maintaining your liver health.
Managing Your OHE Diagnosis
If you’ve been diagnosed with OHE, it’s important to be open with your doctor and loved ones about any challenges you’re facing. Attending all your medical appointments is critical, allowing your doctor to assess whether your current care plan is effective or if adjustments are needed. Your healthcare provider might recommend prescription treatments, significant lifestyle changes like abstaining from alcohol and modifying your diet, or even a liver transplant if your symptoms become severe.
Working closely with your care team, which includes your caregivers, is essential. Caregivers play a vital role by monitoring your symptoms and providing support with appointments and treatment adherence. If you or your caregiver notice any changes in your physical or mental abilities, it’s crucial to contact your healthcare provider immediately.
Introducing XIFAXAN® (rifaximin) 550 mg Tablets
For adults with a history of overt HE, managing the risk of recurrence is a primary concern. XIFAXAN® (rifaximin) 550 mg tablets are FDA-approved for reducing the risk of overt hepatic encephalopathy (HE) recurrence. In clinical studies, XIFAXAN helped cut the risk of HE-related hospitalizations in half compared to a placebo, and significantly reduced breakthrough OHE episodes.
XIFAXAN is taken as a 550 mg tablet twice a day, with or without food, as prescribed by your doctor. It’s important to continue taking XIFAXAN as directed for as long as your doctor determines you are at risk for recurrent OHE. XIFAXAN is recognized as part of the American Association for the Study of Liver Diseases (AASLD) guidelines for OHE management.
- Overt Hepatic Encephalopathy (OHE) is a brain dysfunction linked to severe chronic liver disease (cirrhosis).
- Symptoms can include tremors, confusion, and forgetfulness.
- Close monitoring of symptoms and adherence to treatment plans are key.
- Open communication with your doctor and caregivers is crucial for effective management.
- XIFAXAN® (rifaximin) 550 mg tablets are FDA-approved to reduce the risk of OHE recurrence in adults.
If you or a loved one are dealing with Overt Hepatic Encephalopathy, talk to your doctor about your symptoms and explore all available treatment options. Visit www.xifaxan.com/he to learn more and access resources like a copay savings card.